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Homepage | Sentinel Initiative

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Homepage | Sentinel Initiative

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The U.S. FDA leads the Sentinel Initiative. The main goal is to improve how FDA evaluates the safety and performance of medical products.

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Headings

H1 H2 H3 H4 H5 H6
1 11 12 0 0 0
  • [H1] Learn More About
  • [H2] Sentinel Contributions Now Available
  • [H2] ISPE 2025 Spotlight Poster
  • [H2] Published in Pharmacoepidemiology and Drug Safety
  • [H2] FDA's Sentinel System:
  • [H2] What's Happening with Sentinel
  • [H2] Recent Activity
  • [H2] About Sentinel
  • [H2] Engage with Sentinel
  • [H2] Data-Driven Impact
  • [H2] The Sentinel Community
  • [H2] Sentinel Structure
  • [H3] Calcitonin Gene-Related Peptide (CGRP) Inhibitors & Gastrointestinal Hypomotility, Constipation or GI dysmotility with Serious Complications and Intentional Self-Harm
  • [H3] Risk of Gastrointestinal Hypomotility, Constipation, or GI Dysmotility with Serious Complications and Intentional Self-Harm in Individuals with Migraine Following Use of CGRP Inhibitors: A Propensity Score Matched Analysis
  • [H3] Outcome Monitoring Following Prucalopride and Plecanatide Use: An Active Comparator Signal Identification Analysis with Alternating Exposure-Comparator Roles
  • [H3] Semaglutide Injectables & Signal Identification
  • [H3] Motegrity (Prucalopride) & Signal Identification
  • [H3] How Sentinel Uses Data
  • [H3] How Sentinel Protects Privacy
  • [H3] Where Sentinel Gets Its Data
  • [H3] What Data Sentinel Uses
  • [H3] 16th Annual Sentinel Initiative Public Workshop
  • [H3] Methods, Data, & Tools
  • [H3] Data Partners & Collaborators

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Anchor Type Juice
Skip to main content Interno Passing Juice
About Interno Passing Juice
Who is Involved Interno Passing Juice
Sentinel Structure Interno Passing Juice
Sentinel Innovation Center (IC) Interno Passing Juice
Sentinel Operations Center (SOC) Interno Passing Juice
Engaging Sentinel's Stakeholders Interno Passing Juice
Information For the Public Interno Passing Juice
Information For Providers Interno Passing Juice
How Sentinel Gets Its Data Interno Passing Juice
Key Database Statistics Interno Passing Juice
How Sentinel Protects Privacy & Security Interno Passing Juice
Principles & Policies Interno Passing Juice
Data Interno Passing Juice
Privacy Interno Passing Juice
Confidentiality Interno Passing Juice
Communications Interno Passing Juice
Intellectual Property Interno Passing Juice
Conflict of Interest Interno Passing Juice
Studies Interno Passing Juice
Drugs Interno Passing Juice
Individual Drug Analyses Interno Passing Juice
Assessing ARIA's Ability to Evaluate a Safety Concern Interno Passing Juice
Vaccines, Blood, & Biologics Interno Passing Juice
Devices & Radiological Health Interno Passing Juice
Methods, Data, & Tools Interno Passing Juice
Methods Interno Passing Juice
Sentinel Common Data Model Interno Passing Juice
Signal Identification in the Sentinel System Interno Passing Juice
FAQs Interno Passing Juice
Resources Interno Passing Juice
Use of TreeScan by Non-Sentinel Investigators Interno Passing Juice
Routine Querying Tools Interno Passing Juice
Level 1 Analyses Interno Passing Juice
Level 2 Analyses Interno Passing Juice
Level 3 Analyses Interno Passing Juice
Software Packages & Toolkits Interno Passing Juice
Health Outcomes of Interest Interno Passing Juice
FDA-Catalyst Projects Interno Passing Juice
Sentinel as a National Resource Interno Passing Juice
News & Events Interno Passing Juice
Recent Sentinel Activity Interno Passing Juice
Recent Sentinel Events Interno Passing Juice
Meetings, Workshops, & Trainings Interno Passing Juice
Documents, Presentations, & Publications Interno Passing Juice
FDA Safety Communications & Labeling Changes Interno Passing Juice
FDA Advisory Committee Meetings Interno Passing Juice
Featured Interno Passing Juice
Coronavirus (COVID-19) Interno Passing Juice
Pediatrics Interno Passing Juice
Pregnancy Interno Passing Juice
Race and Ethnicity Interno Passing Juice
Engage with Sentinel Interno Passing Juice
Sentinel Training Center Interno Passing Juice
Contact Interno Passing Juice
Careers Interno Passing Juice
FAQs Interno Passing Juice
How Sentinel Works Interno Passing Juice
Coronavirus (COVID-19) Activities Interno Passing Juice
What's Happening with Sentinel Interno Passing Juice
About Sentinel Interno Passing Juice
Engage with Sentinel Interno Passing Juice
Data-Driven Impact Interno Passing Juice
The Sentinel Community Interno Passing Juice
Sentinel Structure Interno Passing Juice
An Assessment of the Sentinel System (2022 to 2024) Interno Passing Juice
Characterization of Dosage of Attention-Deficit/Hyperactivity Disorder (ADHD) Stimulant Medications: A Descriptive Analysis Interno Passing Juice
Rates of Diabetic Ketoacidosis (DKA) by Chronic Kidney Disease (CKD) Stage Among Patients with Type 1 Diabetes Mellitus (T1DM): A Propensity Score Matched Analysis Interno Passing Juice
Trends in Healthcare Encounters Involving Disorders or Poisoning Related to Cannabis, Stratified by the Legality Status of Cannabis by State and Territory: An Updated Descriptive Analysis Interno Passing Juice
Calcitonin Gene-Related Peptide (CGRP) Inhibitors & Gastrointestinal Hypomotility, Constipation or GI dysmotility with Serious Complications and Intentional Self-Harm Externo Passing Juice
Risk of Gastrointestinal Hypomotility, Constipation, or GI Dysmotility with Serious Complications and Intentional Self-Harm in Individuals with Migraine Following Use of CGRP Inhibitors: A Propensity Score Matched Analysis Externo Passing Juice
Outcome Monitoring Following Prucalopride and Plecanatide Use: An Active Comparator Signal Identification Analysis with Alternating Exposure-Comparator Roles Externo Passing Juice
Semaglutide Injectables & Signal Identification Externo Passing Juice
Motegrity (Prucalopride) & Signal Identification Externo Passing Juice
View Materials Interno Passing Juice
Scientific Publications Interno Passing Juice
Drug Studies Externo Passing Juice
Privacy Policy Interno Passing Juice
Accessibility Interno Passing Juice
Disclaimer Interno Passing Juice
Site Map Interno Passing Juice

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